This is where you can manage most of your account parameters: timesheets, regional settings, global tasks, absences.
Click the top right menu: "Settings"
Settings are defined for your own company or organization.
For example, your main company is in the US, USD is your currency, and 01/25/2011 is your date format.
But you have also a branch in the UK, GBP is their currency and 25/01/2011 is their date format.